Hydrophilic metformin and hydrophobic biguanides inhibit mitochondrial complex I by distinct mechanisms
- Zhaoxiang He
- Fei Teng
- et al.
- 2025
- Nature Structural and Molecular Biology
Paper
Publications
245 results for Ruhong Zhou
Integrating Physics-Based Simulations with Data-Driven Deep Learning Represents a Robust Strategy for Developing Inhibitors Targeting the Main Protease
- Yanqing Yang
- Yangwei Jiang
- et al.
- 2025
- J. Chem. Inf. Model.
PaperMolecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide
- Xiaolong Li
- Nishant Kumar Singh
- et al.
- 2023
- Nature Communications
PaperA mutagenesis study of autoantigen optimization for potential T1D vaccine design
- Yi Song
- David R. Bell
- et al.
- 2023
- PNAS
PaperPossible Co-Evolution of Polyglutamine and Polyproline in Huntingtin Protein: Proline-Rich Domain as Transient Folding Chaperone
- Leili Zhang
- Hongsuk Kang
- et al.
- 2022
- Journal of Physical Chemistry Letters
PaperBinding Affinity Calculations of Gluten Peptides to HLA Risk Modifiers: DQ2.5 versus DQ7.5
- Yi Song
- Sangyun Lee
- et al.
- 2022
- Journal of Physical Chemistry B
PaperDynamics-Based Peptide-MHC Binding Optimization by a Convolutional Variational Autoencoder: A Use-Case Model for CASTELO
- David R. Bell
- Giacomo Domeniconi
- et al.
- 2021
- JCTC
PaperMolecular Insight into AC Electric Field Enhanced Removal of Protein Aggregates from a Material Surface
- Mei Feng
- Sangyun Lee
- et al.
- 2021
- Journal of Physical Chemistry B
PaperDioxybenzone triggers enhanced estrogenic effect via metabolic activation: in silico, in vitro and in vivo investigation
- Tingjie Zhan
- Leili Zhang
- et al.
- 2021
- Environmental Pollution
PaperProteasome activity regulated by charged gold nanoclusters: Implications for neurodegenerative diseases
- Xiaochuan Ma
- Sangyun Lee
- et al.
- 2020
- Nano Today
Paper