Daniel J. Coady, Amanda C. Engler, et al.
ACS Macro Letters
Paper
Broad-spectrum antimicrobial and biofilm-disrupting hydrogels: Stereocomplex-driven supramolecular assemblies
Abstract
Fighting the resistance: Biodegradable and injectable/moldable hydrogels with hierarchical nanostructures (see picture) were made with broad-spectrum antimicrobial activities and biofilm-disruption capability. They demonstrate no cytotoxicity in vitro, and show excellent skin biocompatibility in animals. These hydrogels have great potential for clinical use in prevention and treatment of various multidrug-resistant infections. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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